• Eupatorium Perfoliatum is known as "Bone-set," indicating its effectiveness for bone and muscle pain during fevers.

• Eupatorium Perfoliatum primarily acts on the gastro-hepatic system and bronchial mucous membranes.

• Eupatorium Perfoliatum is indicated in miasmatic regions, especially near rivers and marshes.

• Cachexia is present from chronic, bilious intermittent fevers.

• Eupatorium Perfoliatum is useful for debilitated constitutions due to alcoholism.

• General sluggishness of organs and functions is present.

• Marked soreness is felt throughout the body.

• Significant periodicity of symptoms is observed.

• Eupatorium Perfoliatum acts profoundly on the periosteum and fibrous tissues.

• Symptoms are often associated with bilious conditions.

• Great prostration and weakness are experienced.

•

• Irritability and restlessness are present.

• Mental prostration and apathy are experienced.

• Apprehension and anxiety are present, especially regarding health.

• The patient desires company but is too tired to interact.

• Forgetfulness and difficulty concentrating are present.

• Great depression of spirits is experienced.

• Indifference to everything is present.

• Aversion to conversation is observed.

• Periodical headache occurs every third and seventh day.

• Occipital pain is felt after lying down, with a sensation of weight.

• Headache is accompanied by nausea and vomiting.

• Frontal headache is present, with soreness of the eyeballs.

• Headache is better by sweating.

• Soreness and aching of the eyeballs is present.

• Yellowish tinge is present to the conjunctiva.

• Photophobia (sensitivity to light) is experienced.

• Coryza is present with sneezing and watery discharge.

• Soreness is felt in the nasal passages.

• Sore throat is present with hoarseness.

• Dryness and burning sensation are felt in the throat.

• Rawness is felt in throat on swallowing.

• #

• Deep, racking cough is present with chest soreness.

• Hoarseness and raw feeling are present in the trachea.

• Bronchitis is present with copious expectoration.

• Cough is worse at night.

• Cough is present with soreness behind the sternum.

• Palpitations are experienced, especially during fever.

• Soreness and aching are present in the chest muscles.

• Nausea and vomiting are experienced, especially with headache.

• #

• Thirst for cold drinks is present.

• Bitter taste is present in the mouth.

• Loss of appetite is experienced.

• Craving for acids is present.

• Aversion to sweet things is observed.

• Soreness and tenderness are present in the abdominal muscles.

• Pain is felt in the liver region.

• Enlarged and painful liver is present.

• Abdomen is distended.

• Rectum:

• Constipation is present with hard, dry stools.

• Constipation is present alternating with diarrhea.

• Soreness is felt in the kidneys.

• Frequent urination with burning is experienced.

• Urinary difficulties are associated with fever.

• (Male) Soreness and aching are felt in testicles.

• (Female) Menses are early and profuse.

• (Female) Pain is felt in uterus.

• Soreness and aching are felt in the muscles.

• Heaviness and weakness are felt in the limbs.

• Pain is felt in the back and small of the back.

• Aching is felt in all bones, especially the long bones.

• Backache is relieved by lying on something hard.

• Rheumatic pains are worse in cold, damp weather.

• Bones feel as if they would break.

• Limbs feel bruised.

• Skin is yellowish during fevers.

• Profuse sweating occurs, especially during defervescence.

• Sweat relieves the bone pains.

• Restless sleep is experienced due to bone pains.

• Sleeplessness is experienced before midnight.

• Dreams are vivid and disturbing.

• Morning, cold air, motion, lying down (occipital pain), touch, changes of weather, 7-9 AM.

• #

• Warmth, sweating, rest, lying on the painful side.

• Arsenicum album, Bryonia, China, Gelsemium.

• Camphor, Ipecacuanha.

• #